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Article

Comparison of Anterior Segment Abnormalities in Individuals With FOXC1 and PITX2 Variants.

Cornea - 1 Aug 2022

Prem Senthil Mallika, Knight Lachlan S W, Taranath Deepa, Mackey David A, Ruddle Jonathan B, Chiang Mark Y, Siggs Owen M, Souzeau Emmanuelle, Craig Jamie E

Abstract excerpt

PURPOSE: Axenfeld-Rieger syndrome encompasses a group of developmental disorders affecting the anterior chamber structures of the eye, with associated systemic features in some cases. This study aims to compare the difference in anterior segment phenotypes such as those involving the cornea, iris, lens, and anterior chamber angle between cases with disease-causing sequence variations in FOXC1 and PITX2 . METHODS:...

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Source

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Identifiers

PMID: 35354164
DOI: 10.1097/ICO.0000000000003020
PMCID: PMC9390227

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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