Back to search

Article

MicroRNA-122 : release, uptake and isomiRs in drug-induced liver injury

2021-01-01

Abstract excerpt

microRNAs (miRNAs) are small, non-protein coding RNAs which post-transcriptionally downregulate gene expression. Circulating miRNAs are promising clinical biomarkers, and circulate either within extracellular vesicles (ECVs) or bound to proteins, both of which protect miRNAs against degradation. Recently, small RNA sequencing has demonstrated the existence of isomiRs, of which vary in length and/or sequence when c...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
51967ceb-68d5-5869-a258-495e31589e04
DOI
10.7488/era/1140
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
MicroRNA-122 : release, uptake and isomiRs in drug-induced liver injuryDOI 10.7488/era/1140
Application of High-Throughput Sequencing to Circulating microRNAs Reveals Novel Biomarkers for Drug-Induced Liver InjurySemantic proximity
Circulating miR-122 as a Potential Biomarker of Liver DiseaseSemantic proximity
Unraveling the Mysterious Interactions Between Hepatitis C Virus RNA and Liver-Specific MicroRNA-122Semantic proximity
Multiplex Profiling of miR-122 for Preclinical and Clinical Evaluation of Drug-Induced Liver Injury by a Full-Scale PlatformSemantic proximity
Circulating microRNA-122a as a diagnostic marker for hepatocellular carcinomaSemantic proximity
Serum microRNA signatures as "liquid biopsies" for interrogating hepatotoxic mechanisms and liver pathogenesis in human.Semantic proximity
Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA.Semantic proximity
Circulating miR-122 and miR-200a as biomarkers for fatal liver disease in ART-treated, HIV-1-infected individualsSemantic proximity
Evaluation of miR-122 Serum Level and IFN-λ3 Genotypes in Patients with Chronic HCV and HCV-Infected Liver Transplant Candidate.Semantic proximity
Serum microRNA-122 level correlates with virologic responses to pegylated interferon therapy in chronic hepatitis C.Semantic proximity
Parallel expression profiling of hepatic and serum microRNA-122 associated with clinical features and treatment responses in chronic hepatitis C patientsSemantic proximity
Dysregulated Serum MicroRNA Expression Profile and Potential Biomarkers in Hepatitis C Virus-infected PatientsSemantic proximity
Select a neighboring publication to make it the new centre.