Article

Variola virus is as old as the earliest historical lines of evidence suggest

2022-07-01

Abstract excerpt

Archaeovirology efforts provided a rich portrait of the evolutionary history of variola virus (VARV), the causative agent of smallpox. These studies revealed frequent viral lineage extinction and a relatively recent origin of VARV as a human pathogen (∼ 1,700 years ago, ya). This contrasts with historical records suggesting the presence of smallpox as early as 3,500 ya. By performing an analysis of ancestry compon...

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Literature Corpus work: 511b856a-928f-5176-b69a-bbbce37744dc
DOI: 10.1101/2022.06.28.498054

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