Article

SynAPSeg: A novel dataset and image analysis framework for deep learning-based synapse detection and quantification

2026-03-16

Abstract excerpt

Synapses are the fundamental units of neural computation, yet quantifying their organization across circuit-level scales remains a critical bottleneck in neuroscience. While advances in fluorescent labeling and imaging can generate vast datasets, analysis is often the limiting factor. Several deep learning-based tools have been proposed to ameliorate these issues. However, existing applications primarily focus on...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 511303d0-7b2f-52b4-a268-7b1f9b009a14
DOI: 10.64898/2026.03.12.711395

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

SynAPSeg: A novel dataset and image analysis framework for deep learning-based synapse detection and quantificationDOI 10.64898/2026.03.12.711395Read

SynBot: An open-source image analysis software for automated quantification of synapsesSemantic proximity Read

Fully automated detection of dendritic spines in 3D live cell imaging data using deep convolutional neural networksSemantic proximity Read

SynQuant: An Automatic Tool to Quantify Synapses from Microscopy ImagesSemantic proximity Read

The human and mouse synaptome architecture of excitatory synapses show conserved featuresSemantic proximity Read

Sparse Annotation is Sufficient for Bootstrapping Dense Neuron SegmentationSemantic proximity Read

Regional and LTP-Dependent Variation of Synaptic Information Storage Capacity in Rat HippocampusSemantic proximity Read

Synaptic Signatures and Disease Vulnerabilities of Layer 5 Pyramidal NeuronsSemantic proximity Read

Brain-wide Organization of Post-Synaptic Sites: Three PrinciplesSemantic proximity Read

Curvature-based machine learning method for automated segmentation of dendritic spinesSemantic proximity Read

Morphological analysis of human and mouse dendritic spines reveals a morphological continuum and differences across ages and speciesSemantic proximity Read

Quantitative synapse analysis for cell-type specific connectomicsSemantic proximity Read

Toolkits for detailed and high-throughput interrogation of synapses in <i>C. elegans</i>Semantic proximity Read