Article

SynBot: An open-source image analysis software for automated quantification of synapses

2023-06-28

Abstract excerpt

The formation of precise numbers of neuronal connections, known as synapses, is crucial for brain function. Therefore, synaptogenesis mechanisms have been one of the main focuses of neuroscience. Immunohistochemistry is a common tool for visualizing synapses. Thus, quantifying the numbers of synapses from light microscopy images enables screening the impacts of experimental manipulations on synapse development. De...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 483f594b-6764-5dc6-bccc-f99943333f02
DOI: 10.1101/2023.06.26.546578

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

SynBot: An open-source image analysis software for automated quantification of synapsesDOI 10.1101/2023.06.26.546578Read

SynQuant: An Automatic Tool to Quantify Synapses from Microscopy ImagesSemantic proximity Read

The human and mouse synaptome architecture of excitatory synapses show conserved featuresSemantic proximity Read

SynAPSeg: A novel dataset and image analysis framework for deep learning-based synapse detection and quantificationSemantic proximity Read

Toolkits for detailed and high-throughput interrogation of synapses in <i>C. elegans</i>Semantic proximity Read

Quantitative synapse analysis for cell-type specific connectomicsSemantic proximity Read

SynaptopathyDB: a resource for studying the genetic and synaptic basis of nervous system disordersSemantic proximity Read

Data-driven synapse classification reveals a logic of glutamate receptor diversitySemantic proximity Read

Visualizing synaptic plasticity in vivo by large-scale imaging of endogenous AMPA receptorsSemantic proximity Read

An automated high-content synaptic phenotyping platform in human neurons and astrocytes reveals a role for BET proteins in synapse assemblySemantic proximity Read

Synaptic Signatures and Disease Vulnerabilities of Layer 5 Pyramidal NeuronsSemantic proximity Read

Proteomics of brain synapses and molecular dissection of synaptic subdomains.Semantic proximity Read

Cell-type specific visualization and biochemical isolation of endogenous synaptic proteins in miceSemantic proximity Read