Article

Gene expression analysis of telomerase related genes in myeloid malignancy

2012-01-01

Abstract excerpt

Telomere shortening and an increased telomerase activity are associated with poor prognosis and disease progression in many cancers. In Chronic Myeloid Leukaemia (CML) telomere shortening has a strong correlation with disease progression. Expression of <i>hTERT</i>, the catalytic component of telomerase, was evaluated in the CD34+ cells of CML patients. This revealed that expression of <i>hTERT</i> was significant...

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Literature Corpus work: 50c8bc03-824b-5c9e-8f49-d1d43760eb78
DOI: 10.21954/ou.ro.0000f15a

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