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Telomerase activity and the expression of telomerase components in acute myelogenous leukaemia

1 Sept 1998

Abstract excerpt

In 95 leukaemic cell samples from 66 patients with acute myelogenous leukaemia (AML) (47 de novo and 19 secondary AML) telomerase activity was determined and the expression of the telomerase components: telomerase reverse transcriptase (hTERT), telomerase RNA template (hTR) and telomerase-associated protein (TP1) evaluated by RT-PCR. Compared to peripheral blood mononuclear cells (PBMC) from normal adult 87%...

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Share to Advanced biosensing and bioanalysis techniques
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Share to Telomeres, Telomerase, and Senescence

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Identifiers

PMID: 9753073
DOI: 10.1046/j.1365-2141.1998.00969.x

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