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Article

hTERT, the catalytic component of telomerase, is downregulated in the haematopoietic stem cells of patients with chronic myeloid leukaemia

23 Feb 2006

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Share to Cancer Cells and Metastasis
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Share to Telomeres, Telomerase, and Senescence

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 16498395
DOI: 10.1038/sj.leu.2404141

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hTERT, the catalytic component of telomerase, is downregulated in the haematopoietic stem cells of patients with chronic myeloid leukaemiaPMID 16498395Read ↗

Mechanism of Human Telomerase Reverse Transcriptase (hTERT) Regulation and Clinical Impacts in LeukemiaSemantic proximity Read ↗

hEST2, the Putative Human Telomerase Catalytic Subunit Gene, Is Up-Regulated in Tumor Cells and during ImmortalizationSemantic proximity Read ↗

hTERT associates with human telomeres and enhances genomic stability and DNA repairSemantic proximity Read ↗

Differential gene expression of human telomerase-associated protein hTERT and TEP1 in human hematopoietic cellsSemantic proximity Read ↗

Telomerase activity and cytogenetic changes in chronic myeloid leukemia with disease progressionSemantic proximity Read ↗

The significance of human telomerase reverse transcriptase (hTERT) in cancerSemantic proximity Read ↗

Gene expression analysis of telomerase related genes in myeloid malignancySemantic proximity Read ↗

Demethylation of the human telomerase catalytic subunit (hTERT) gene promoter reduced hTERT expression and telomerase activity and shortened telomeresSemantic proximity Read ↗

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Telomerase Inhibition Effectively Targets Mouse and Human AML Stem Cells and Delays Relapse following ChemotherapySemantic proximity Read ↗

Telomeres and telomerase in chronic myeloid leukaemia: impact for pathogenesis, disease progression and targeted therapySemantic proximity Read ↗

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