Article

Anti-angiogenic effects of VEGF stimulation on endothelium deficient in phosphoinositide recycling

2018-08-28

Abstract excerpt

Anti-angiogenic therapies have generated significant interest for their potential to combat tumor growth ( 1-6 ). However, the ability of tumors to overproduce pro-angiogenic ligands and overcome targeted inhibitory therapies has hampered this approach ( 7, 8 ). A novel way to circumvent this problem might be to target the resynthesis of critical substrates consumed during intracellular transduction of pro-angio...

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Literature Corpus work: 508955d7-8163-5b55-9651-0231b925a469
DOI: 10.1101/402362

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