Article
Incorporating G6PD genotyping to identify patients with G6PD deficiency.
Pharmacogenetics and genomics - 1 Apr 2022
Morris Sarah A, Crews Kristine R, Hayden Randall T, Takemoto Clifford M, Yang Wenjian, Baker Donald K, Broeckel Ulrich, Relling Mary V, Haidar Cyrine E
Abstract excerpt
Glucose-6-phosphate-dehydrogenase (G6PD) deficiency is a common X-linked enzyme disorder associated with hemolytic anemia after exposure to fava beans or certain medications. Activity testing is the gold standard for detecting G6PD deficiency; however, this test is affected by various hematologic parameters. Clinical G6PD genotyping is now included in pharmacogenetic arrays and clinical sequencing efforts and may...
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