Article

Mutations in Filamin C Associated With Both Alleles do not Affect the Functioning of Mice Cardiac Muscles

2024-11-18

Abstract excerpt

Filamin C (FLNC) is a structural protein of muscle fibers. Mutations in the Flnc gene are known to cause myopathies and cardiomyopathies in humans. Here we report a generation of two mouse strains carrying filamin C mutations — one of them has a deletion of three nucleotides at position c.7418_7420, causing E>>;D substitution and N deletion at positions 2472 and 2473, respectively. The other strain carries a...

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Literature Corpus work: 50626664-db7b-5d4e-a0e6-4e0aedf808e3
DOI: 10.20944/preprints202411.1229.v1

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Mutations in Filamin C Associated With Both Alleles do not Affect the Functioning of Mice Cardiac MusclesDOI 10.20944/preprints202411.1229.v1Read

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