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Structural Adaptations of HepI Enzymes in Proteobacteria: Insights into Evolutionary Resilience and Functional Dynamics

2024-09-02

Abstract excerpt

Since lipopolysaccharide molecules are highly variable in their structure while also being essential for bacterial cell survival, we hypothesized that enzymes involved in its biosynthesis may exhibit differences that could be used to predict the likelihood of survival in different ecological niches. We examined the sequence variability of orthologues of Heptosyltransferase I (HepI), which is found in all lipopolys...

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Literature Corpus work
50420015-ab01-50c7-8e32-0088eb7ea56c
DOI
10.1101/2024.09.01.610683
Open publication

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Structural Adaptations of HepI Enzymes in Proteobacteria: Insights into Evolutionary Resilience and Functional DynamicsDOI 10.1101/2024.09.01.610683
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