Article

Improved <i>in silico</i> and <i>in vitro</i> methods for <i>E. coli</i> LPS outer core typing

2025-04-13

Abstract excerpt

The Gram-negative bacterial envelope comprises the outer membrane, periplasmic space with the peptidoglycan layer, and inner (cytoplasmic) membrane. A lipopolysaccharide (LPS) layer linked to the outer membrane is essential for survival in most species of bacteria, primarily by providing structural stability and regulating selective chemical permeability. These functions make the LPS layer a key pathogenicity dete...

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Literature Corpus work: f5661282-1702-53cf-a49a-19e998f884dd
DOI: 10.1101/2025.04.13.648558

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