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Advances in Helicobacter pylori lipopolysaccharide structure and function

1 Jan 2025

Abstract excerpt

Helicobacter pylori is a widespread pathogen responsible for chronic gastritis, peptic ulcers, and an elevated risk of gastric cancer. Lipopolysaccharide (LPS), localized exclusively in the outer leaflet of the outer membrane, is essential for maintaining bacterial integrity. Recent advances have deepened our understanding of H. pylori LPS structure, particularly lipid A modifications and the redefinition of the...

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PMID: 40720770
DOI: 10.1093/femsre/fuaf034

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