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Ultra-sensitivity metaproteomics redefines the gut “dark metaproteome”, uncovering host-microbiome interactions and drug targets in intestinal inflammatory diseases

2024-04-22

Abstract excerpt

<h4>ABSTRACT</h4> The gut microbiome is a complex ecosystem with significant inter-individual variability determined by hundreds of low-abundant species as revealed by genomic methods. Functional redundancy demands direct quantification of microbial biological functions to understand their influence on host physiology. This functional landscape remains unexplored due to limited sensitivity in metaproteomics metho...

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Literature Corpus work
432cde85-37d6-5420-b8f1-d9db34944f2d
DOI
10.1101/2024.04.22.590295
Open publication

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Ultra-sensitivity metaproteomics redefines the gut “dark metaproteome”, uncovering host-microbiome interactions and drug targets in intestinal inflammatory diseasesDOI 10.1101/2024.04.22.590295
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