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Integrative analysis reveals an indirect connection between COX-2/PTGS2 and extracellular matrix proteins in Ch11q-deleted neuroblastoma

2021-05-27

Abstract excerpt

The COX-2 protein, encoded by the PTGS2 gene, is related to tumor progression in adult and pediatric cancer. In neuroblastoma (NB), COX-2 was associated with loss of heterozygosity on the long arm of chromosome 11 (Ch11q loss of heterozygosity, LOH), defining a subset of aggressive disease. The present study aimed to investigate the protein expression of COX-2 in a set of 82 pre-chemotherapy (CT) and 20 post-CT NB...

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Literature Corpus work
4f9b9a78-ffe5-5ba5-8ba1-fe930f36a64e
DOI
10.22541/au.162212567.71149689/v1
Open publication

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Integrative analysis reveals an indirect connection between COX-2/PTGS2 and extracellular matrix proteins in Ch11q-deleted neuroblastomaDOI 10.22541/au.162212567.71149689/v1
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