Article

Discovering Key Transcriptomic Regulators in Pancreatic Ductal Adenocarcinoma using Dirichlet Process Gaussian Mixture Model

2020-10-02

Abstract excerpt

<h4>ABSTRACT</h4> Pancreatic Ductal Adenocarcinoma (PDAC) is the most lethal type of pancreatic cancer (PC), late detection of which leads to its therapeutic failure. This study aims to find out key regulatory genes and their impact on the progression of the disease helping the etiology of the disease which is still largely unknown. We leverage the landmark advantages of time-series gene expression data of this d...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 4f866fb3-c2bd-5bd7-92ff-102095fbb13e
DOI: 10.1101/2020.10.01.322768

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 10 closest

Discovering Key Transcriptomic Regulators in Pancreatic Ductal Adenocarcinoma using Dirichlet Process Gaussian Mixture ModelDOI 10.1101/2020.10.01.322768Read

Integrated Bioinformatics Analysis of Gene Expression Profiles for Potential Biomarker Identification Towards Early Therapeutic Intervention in Pancreatitis and Pancreatic ductal adenocarcinomaSemantic proximity Read

Expression profiles analysis of pancreatic cancer.Semantic proximity Read

Identification of Key Regulators in Pancreatic Ductal Adenocarcinoma using Network theoretical ApproachSemantic proximity Read

Identify key genes and pathways in pancreatic ductal adenocarcinoma via bioinformatics analysisSemantic proximity Read

Analysis of dynamic molecular networks for pancreatic ductal adenocarcinoma progressionSemantic proximity Read

Polymorphisms in transcription factor binding sites and enhancer regions and pancreatic ductal adenocarcinoma risk.Semantic proximity Read

A Novel Unsupervised Algorithm for Biological Process-based Analysis on Cancer.Semantic proximity Read

Systematic analysis on expression quantitative trait loci identifies a novel regulatory variant in ring finger and WD repeat domain 3 associated with prognosis of pancreatic cancerSemantic proximity Read

Characterization of histone modification patterns and prediction of novel promoters using functional principal component analysis.Semantic proximity Read

A new genome-wide method to identify genes with bimodal gene expressionSemantic proximity Read