Article
Characterization of histone modification patterns and prediction of novel promoters using functional principal component analysis.
PloS one - 1 Jan 2020
Kim Mijeong, Lin Shili
Abstract excerpt
Characterization of distinct histone methylation and acetylation binding patterns in promoters and prediction of novel regulatory regions remains an important area of genomic research, as it is hypothesized that distinct chromatin signatures may specify unique genomic functions. However, methods that have been proposed in the literature are either descriptive in nature or are fully parametric and hence more...
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