Article

Context-Aware Prediction of Pathogenicity of Missense Mutations Involved in Human Disease

2017-01-25

Abstract excerpt

Amino-acid substitutions are implicated in a wide range of human diseases, many of which are lethal. Distinguishing such mutations from polymorphisms without significant effect on human health is a necessary step in understanding the etiology of such diseases. Computational methods can be used to select interesting mutations within a larger set, to corroborate experimental findings and to elucidate the cause of th...

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Literature Corpus work: 4f7ed9f4-532a-550f-b27f-503b6fbd5d03
DOI: 10.1101/103051

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