Article

Cell-free glycoengineering of the recombinant SARS-CoV-2 spike glycoprotein

2021-04-30

Abstract excerpt

The baculovirus-insect cell expression system is readily utilized to produce viral glycoproteins for research as well as for subunit vaccines and vaccine candidates, for instance against SARS-CoV-2 infections. However, the glycoforms of recombinant proteins derived from this expression system are inherently different from mammalian cell-derived glycoforms with mainly complex-type N -glycans attached, and the impa...

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Literature Corpus work: 4f3b8f3d-5dba-592f-b45d-ed7b11a22e26
DOI: 10.1101/2021.04.30.442139

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