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Outcomes of CyberKnife Stereotactic Radiosurgery for the Brain Metastases in Patients with Li Fraumeni Syndrome

2026-04-09

Abstract excerpt

<title>Abstract</title> <p> Background Li-Fraumeni syndrome (LFS) is a hereditary cancer predisposition syndrome associated with germline <italic>TP53</italic> mutations and an increased risk of radiation-induced malignancies, posing significant challenges in the management of brain metastases (BM). Data regarding the safety and efficacy of stereotactic radiosurgery (SRS) for BM in this population remain limi...

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Literature Corpus work
4f20b85c-f626-532d-8287-5fd5c2fe0af9
DOI
10.21203/rs.3.rs-9295398/v1
Open publication

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