Article

Interferons drive development of novel interleukin-15-responsive macrophages

2019-06-06

Abstract excerpt

<h4>ABSTRACT</h4> Disruption in homeostasis of interleukin-15 (IL-15) is linked to poor maternal and fetal outcomes during pregnancy. The only cells described to respond to IL-15 at the early maternal-fetal interface have been natural killer (NK) cells. We now show a novel population of macrophages, evident in several organs but enriched in the uterus of mice and humans, expressing the β chain of the IL-15 recept...

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Literature Corpus work: 4f1531af-4eab-5ba8-8d25-ca7f8cb5f349
DOI: 10.1101/663476

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