Article
Immune status of decidual macrophages is dependent on the CCL2/CCR2/JAK2 pathway during early pregnancy.
American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Nov 2021
Wei Chun-Yan, Li Ming-Qing, Zhu Xiao-Yong, Li Da-Jin
Abstract excerpt
PROBLEM: Decidual macrophages (dMφ ) play an important role in the formation of maternal-fetal immune tolerance. However, factors that influence the immune status of dMφ and the related potential mechanisms have not been elucidated to date. METHOD OF STUDY: The gene transcription in dMφ , decidual stromal cells (DSCs), extravillous trophoblasts (EVTs), and peripheral monocytes (pMo) from human samples were...
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