Article

Benchmarking taxonomic classifiers with Illumina and Nanopore sequence data for clinical metagenomic diagnostic applications

2022-01-13

Abstract excerpt

Culture-independent metagenomic detection of microbial species has the potential to provide rapid and precise real-time diagnostic results. However, it is potentially limited by sequencing and classification errors. We use simulated and real-world data to benchmark rates of species misclassification using 100 reference genomes for each of ten common bloodstream pathogens and six frequent blood culture contaminants...

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Literature Corpus work: 4ed81b36-581e-5b83-8dff-dfe4c80a1dcd
DOI: 10.1101/2022.01.11.475979

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