Article

Integrative Profiling of Glymphatic Dysfunction in Adolescent Subthreshold Depression

2025-12-27

Abstract excerpt

<h4>Objective</h4> Subthreshold depression (StD) in adolescence is a potent risk factor for major depressive disorder, yet its neurobiological mechanisms remain unclear. The glymphatic system, a brain-wide waste clearance pathway, has been implicated in psychiatric disorders but has not been investigated integratively in StD. This study aimed to characterize glymphatic function in adolescents with StD using a mul...

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Literature Corpus work: 4ed1e408-4695-58ae-a602-92708c278ca8
DOI: 10.64898/2025.12.18.25342437

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