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Heterologous prime-boost regimen elicits potent humoral and cell-mediated immune responses and provides complete protection against SFTSV

2023-01-09

Abstract excerpt

Severe Fever with Thrombocytopenia Syndrome Virus(SFTSV) was first discovered in 2009 as the causative agent of severe fever with thrombocytopenia syndrome. Despite its potential threat to public health, no prophylactic vaccine is yet available. This study developed a heterologous prime-boost strategy comprising priming with recombinant replication-deficient human adenovirus type 5 (rAd5) expressing the surface gl...

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Literature Corpus work
4ecae9a7-87e8-5e72-b07e-e3cfc0da0d0e
DOI
10.21203/rs.3.rs-2420776/v1
Open publication

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