Article

Inferring large networks with matrix factorisation to capture non-linear dependencies among genes using sparse single-cell profiles

2026-03-10

Abstract excerpt

Inference of non-linear dependencies among a large number of features from their scores is an unresolved challenge. Especially when the feature-score matrix is very sparse, like single-cell transcriptome profiles, the problem of estimating dependencies among a large number of features to infer a network becomes an even more daunting task. Here, we propose a method of network inference in reduced dimension (NIRD) t...

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Literature Corpus work: 4ea8a493-b97c-5dfb-b203-70e72211f200
DOI: 10.64898/2026.03.08.710347

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