Article

Pharyngeal carriage of inoculated recombinant commensal bacteria generates antigen-specific immunological memory

2020-05-10

Abstract excerpt

<h4>ABSTRACT</h4> The human nasopharynx is colonized by commensal bacteria and pathobionts, which comprise a complex microbial ecosystem capable of generating primary and secondary immune responses. Experimental intranasal infection of human adults with the commensal Neisseria lactamica results in safe, sustained colonization. Herein is described a novel technology to chromosomally transform N. lactamica with hete...

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Literature Corpus work: 4e8337bc-7ac8-52ca-bf59-0e2100da0d37
DOI: 10.1101/2020.05.06.20093450

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