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Cellular barcoding of protozoan pathogens reveals the within-host population dynamics of <i>Toxoplasma gondii</i> host colonization

2020-08-07

Abstract excerpt

Molecular barcoding techniques have emerged as powerful tools to understand microbial pathogenesis. However, barcoding strategies have not been extended to protozoan parasites, which have unique genomic structures and virulence strategies compared to viral and bacterial pathogens. Here, we present a versatile CRISPR-based method to barcode protozoa, which we successfully apply to Toxoplasma gondii and Trypanosom...

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Literature Corpus work
4e621a5d-378a-55b3-9718-c6673f18fee5
DOI
10.1101/2020.08.06.239822
Open publication

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Cellular barcoding of protozoan pathogens reveals the within-host population dynamics of <i>Toxoplasma gondii</i> host colonizationDOI 10.1101/2020.08.06.239822
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