Article

OGUs enable effective, phylogeny-aware analysis of even shallow metagenome community structures

2021-04-06

Abstract excerpt

We introduce Operational Genomic Unit (OGU), a metagenome analysis strategy that directly exploits sequence alignment hits to individual reference genomes as the minimum unit for assessing the diversity of microbial communities and their relevance to environmental factors. This approach is independent from taxonomic classification, granting the possibility of maximal resolution of community composition, and organi...

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Literature Corpus work: 4e3b168f-2c2f-5ac5-94ca-f4c587e76e79
DOI: 10.1101/2021.04.04.438427

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