Article

Mass Spectrometry for the Analysis of Payloads and Related Impurities in Antibody–Drug Conjugates

2026-04-16

Abstract excerpt

<title>Abstract</title> <p>In antibody–drug conjugate research, the small molecule impurities requiring evaluation include not only free payloads, but also potential payload-related small molecule impurities. In this study, high-resolution mass spectrometry and triple quadrupole mass spectrometry were employed for systematically and comprehensively investigate small molecule related impurities in antibody–drug co...

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Literature Corpus work: 4e324582-cd04-5174-ba5d-93a0f6ada5a1
DOI: 10.21203/rs.3.rs-9212596/v1

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