Article

Personalized Multi-Drug Combinations in Breast Cancer Treatment Using Individual Pattern of Perturbed Gene Expression and Drug Signatures

2021-08-26

Abstract excerpt

The greatest challenge in recent years in cancer treatment has been drug screening. Few platforms presented reliable solutions for personalized drug validation and safety testing. Here, we constructed a personalized drug combination protocol as the primary input to such platforms. We used public data from whole-genome expression profiles of 6173 breast cancer patients, 312 healthy individuals, and 691 drugs. We de...

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Literature Corpus work: 4e23112e-fb90-5592-aeda-9906fa1e67f3
DOI: 10.21203/rs.3.rs-812373/v1

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