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Host and environmental determinants of human milk oligosaccharides and microbiota in the Lifelines NEXT cohort

1 Aug 2025

Abstract excerpt

Human milk is important for infant development, but few large studies have comprehensively investigated milk composition. Here, we characterized human milk oligosaccharides (HMOs) and milk microbiota, their shaping factors, and their links to infant gut microbiota in the longitudinal Dutch Lifelines NEXT cohort. We measured 24 HMOs in 1,542 milk samples from 524 mothers at 0.5-6 months postpartum, profiled...

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PMID: 40783943
DOI: 10.1016/j.celrep.2025.116124

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