Article

Time-to-Event Analyses of UPDRS and MDS-UPDRS Motor Examination and Functional Outcomes in Early Parkinson’s Disease Clinical Trials

2026-06-28

Abstract excerpt

<title>Abstract</title> <p>Clinical trials in untreated Parkinson’s Disease test therapeutics aimed at improving underlying disease pathophysiology, but inevitably risk the confounding of study results by treatment initiation. Milder clinical features, relative functional preservation and slow progression also raise questions as to how a meaningful benefit can be demonstrated in the period before treatment begins...

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Literature Corpus work: 4de8bb11-0481-5a66-bc62-687a8e65fd60
DOI: 10.21203/rs.3.rs-10021801/v1

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