Article

miRNA Dysregulation in Traumatic Brain Injury and Epilepsy: A Systematic Review to Identify Putative Biomarkers for Post-Traumatic Epilepsy

2022-09-09

Abstract excerpt

<title>Abstract</title> <p>Traumatic brain injury (TBI) leads to Post-traumatic epilepsy (PTE), hence both TBI and PTE share various similar molecular mechanisms. MicroRNA (miRNA) is a small non-coding RNA that acts as a gene silencing molecule. Notably, the dysregulation of miRNAs in various neurological diseases including TBI and epilepsy is reported in several studies. However, studies on commonly dysregulated...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 4dcb339a-85aa-56bd-b532-8ee016580221
DOI: 10.21203/rs.3.rs-1843755/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

miRNA Dysregulation in Traumatic Brain Injury and Epilepsy: A Systematic Review to Identify Putative Biomarkers for Post-Traumatic EpilepsyDOI 10.21203/rs.3.rs-1843755/v1Read

MicroRNAs: The New Challenge for Traumatic Brain Injury DiagnosisSemantic proximity Read

An Overview on the Use of miRNAs as Possible Forensic Biomarkers for the Diagnosis of Traumatic Brain InjurySemantic proximity Read

Exploring the pathogenesis of traumatic brain injury and traumatic epilepsy based on bioinformatics analysisSemantic proximity Read

Analysis of miRNA Expression Profiles in Traumatic Brain Injury (TBI) and Their Correlation with Survival and Severity of InjurySemantic proximity Read

Construction of miRNA-mRNA Regulatory Network Based on Differentially Expressed Genes in Traumatic Brain Injury Rats with Antidepressant TreatmentSemantic proximity Read

Traumatic Brain Injury Dysregulates MicroRNAs to Modulate Cell Signaling in Rat HippocampusSemantic proximity Read

Plasma Exosome-derived MicroRNAs as Novel Biomarkers of Traumatic Brain Injury in RatsSemantic proximity Read

Evidence linking microRNA suppression of essential prosurvival genes with hippocampal cell death after traumatic brain injurySemantic proximity Read

miR-9-5p is downregulated in serum extracellular vesicles of patients treated with biperiden after traumatic brain injurySemantic proximity Read

Systematic review and meta-analysis of differentially expressed miRNAs in experimental and human temporal lobe epilepsy.Semantic proximity Read

Bioinformatic analysis of brain-specific miRNAs for identification of candidate traumatic brain injury blood biomarkersSemantic proximity Read

A Panel of Serum MiRNA Biomarkers for the Diagnosis of Severe to Mild Traumatic Brain Injury in HumansSemantic proximity Read