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Article

Bioinformatic analysis of brain-specific miRNAs for identification of candidate traumatic brain injury blood biomarkers

2019-10-07

Abstract excerpt

<h4>Background</h4> Detection of brain-specific miRNAs in the peripheral blood could serve as a surrogate marker of traumatic brain injury (TBI). Here, we systematically identified brain-enriched miRNAs, and tested their utility for use as TBI biomarkers in the acute phase of care. <h4>Methods</h4> Publically-available microarray data generated from 31 postmortem human tissues was used to rank 1,364 miRNAs in te...

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Literature Corpus work
bd319fa4-6a56-5025-9354-98c6d30764e6
DOI
10.1101/794321
Open publication

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Bioinformatic analysis of brain-specific miRNAs for identification of candidate traumatic brain injury blood biomarkersDOI 10.1101/794321
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