Article

Mendelian randomization analyses support causal relationships between blood metabolites and the gut microbiome

2020-07-01

Abstract excerpt

The gut microbiome has been implicated in a variety of physiological states, but controversy over causality remains unresolved. Here, we performed bidirectional Mendelian randomization (MR) analyses on 3,432 Chinese individuals with whole genome, whole metagenome, anthropometric, and blood metabolic trait data. We identified 58 causal relationships between the gut microbiome and blood metabolites, and replicated 4...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 4da256bc-de62-5112-a380-fbabded2eb1d
DOI: 10.1101/2020.06.30.181438

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Mendelian randomization analyses support causal relationships between blood metabolites and the gut microbiomeDOI 10.1101/2020.06.30.181438Read

Mendelian randomization analyses support causal relationships between blood metabolites and the gut microbiome.Semantic proximity Read

Causal associations between gut microbiome and cardiovascular disease: A Mendelian randomization studySemantic proximity Read

Gut microbiota causally affects drug-induced liver injury via plasma metabolites: a Mendelian randomization studySemantic proximity Read

Causal relationships between gut microbrome and digestive system diseases: A two-sample Mendelian randomization studySemantic proximity Read

Causality of the gut microbiome and atherosclerosis-related lipids: a bidirectional Mendelian Randomization studySemantic proximity Read

Altered Gut Microbiota as a Potential Risk Factor for Coronary Artery Disease in Diabetes: A Two-Sample Bi-Directional Mendelian Randomization StudySemantic proximity Read

Altered Gut Microbiota as a Potential Risk Factor for Coronary Artery Disease in Diabetes: A Two-Sample Bi-Directional Mendelian Randomization StudySemantic proximity Read

Investigating causal associations among gut microbiota, metabolites, and liver diseases: a Mendelian randomization studySemantic proximity Read

Gut microbiota, circulating metabolites, and gallstone disease: a Mendelian randomization studySemantic proximity Read

Mendelian randomization analyses support causal relationships between gut microbiome and longevitySemantic proximity Read

Causal relationships between gut microbrome and digestive system diseases: a two-sample Mendelian Randomization studySemantic proximity Read

Causal Associations between Gut Microbiota and Different Types of Dyslipidemia: A Two-Sample Mendelian Randomization StudySemantic proximity Read