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Carbapenem-resistant Klebsiella pneumoniae (CRKP) transfers conjugative plasmids containing blaNDM-5 and mcr-1 genes via outer membrane vesicles (OMVs)

2022-11-08

Abstract excerpt

A carbapenem-resistant Klebsiella pneumoniae (CRKP) strain, NFYY0065, was isolated from a fecal sample obtained from hospitalized patients in Nanfang hospital. By performing whole genome sequencing (WGS), we revealed that NFYY0065 harbored blaNDM-5 and mcr-1 genes, which were located on the IncX3 plasmid (pAN65-3) and IncHI2 plasmid (pAN65-1), respectively. Transfer of the blaNDM-5-bearing plasmid and mcr-1-bearin...

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Literature Corpus work: 4d7b396f-ca63-5f68-b5f0-63e67de1b533
DOI: 10.21203/rs.3.rs-2234437/v1

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