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Molecular characterization and comparison of bla NDM-1 -carrying and bla NDM-5 -harboring IncX3-type plasmids in carbapenem-resistant Klebsiella pneumoniae

25 Aug 2023

Abstract excerpt

ABSTRACT Carbapenem-resistant Klebsiella pneumoniae (CRKP), which harbors the bla NDM plasmid, has been reported extensively and is considered a global threat clinically. However, characterization and comparisons of bla NDM-1 -carrying and bla NDM-5 -harboring IncX3-type plasmids in CRKP are lacking. Here, we systematically compared the differences in the characteristics, genetic backgrounds, transferability, and...

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PMID: 37623430
DOI: 10.1128/spectrum.01028-23

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