Article

Patient-derived organoids from malignant pleural effusion to explore for alternative therapies in thoracic tumors

2026-03-06

Abstract excerpt

<h4>ABSTRACT</h4> Thoracic malignancies, including lung adenocarcinoma (ADC) and malignant pleural mesothelioma (MPM), remain associated with poor prognosis and limited durable therapeutic responses in advanced stages. Although targeted therapies and immunotherapy have improved outcomes in selected patients, systemic chemotherapy continues to play a central role in routine clinical practice. However, treatment re...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 4d575be7-6c43-51c7-aa55-f165165735a7
DOI: 10.64898/2026.03.04.709498

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Patient-derived organoids from malignant pleural effusion to explore for alternative therapies in thoracic tumorsDOI 10.64898/2026.03.04.709498Read

<em>Ex Vivo</em> Drug Testing of Patient-Derived Lung Organoids to Predict Treatment Responses for Personalized MedicineSemantic proximity Read

Human Lung Adenocarcinoma-Derived Organoid Models for Drug ScreeningSemantic proximity Read

Human lung adenocarcinoma cell cultures derived from malignant pleural effusions as model system to predict patients chemosensitivity.Semantic proximity Read

Culture and multiomic analysis of lung cancer patient-derived pleural effusions revealed distinct druggable molecular types.Semantic proximity Read

An optimized method to culture human primary lung tumor cell spheroidsSemantic proximity Read

Genomic characteristics and drug screening among organoids derived from non‐small cell lung cancer patientsSemantic proximity Read

Patient-derived lung cancer organoids as in vitro cancer models for therapeutic screeningSemantic proximity Read

Patient-Derived Cells to Guide Targeted Therapy for Advanced Lung Adenocarcinoma.Semantic proximity Read

Pleural effusion in lung cancer: more questions than answers.Semantic proximity Read

Patient-derived tumor organoids from resected non-small cell lung cancers for high-throughput response testing with approved and repurposed drugsSemantic proximity Read

Re-Evaluating Breast Malignant Pleural Effusion: Toward Evidence-Based, Precision-Aligned Care with OrganoidsSemantic proximity Read

Re-Evaluating Breast Malignant Pleural Effusion: Toward Evidence-Based, Precision-Aligned Care with OrganoidsSemantic proximity Read