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Biotransformation of docosahexaenoic acid into 10R,17S- dihydroxydocosahexaenoic acid as protectin Dx 10-epimer by serial reactions of arachidonate 8R- and 15S-lipoxygenases

2023-11-16

Abstract excerpt

<title>Abstract</title> <p>Protectins, 10,17-dihydroxydocosahexaenoic acids (10,17-DiHDHAs), are belonged to specialized pro-resolving mediators (SPMs). Protectins are generated by polymorphonuclear leukocytes in humans and resolve inflammation and infection in trace amounts. However, the quantitative production of protectin Dx 10-epimer (10-epi PDX, 10<italic>R</italic>,17<italic>S</italic>-4<italic>Z</italic>,7...

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Literature Corpus work
93da32e0-1561-5378-9c4e-bd0361be57c8
DOI
10.21203/rs.3.rs-3608550/v1
Open publication

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Biotransformation of docosahexaenoic acid into 10R,17S- dihydroxydocosahexaenoic acid as protectin Dx 10-epimer by serial reactions of arachidonate 8R- and 15S-lipoxygenasesDOI 10.21203/rs.3.rs-3608550/v1
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