Article

Label-free Machine Learning Prediction of Chemotherapy on Tumor Spheroids using a Microfluidics Droplet Platform

2025-03-28

Abstract excerpt

To rapidly evaluate the effects of anticancer treatments in 3D models, an integrated approach is proposed, combining a droplet-based microfluidic platform for spheroid formation and single-spheroid chemotherapy application, label-free morphological analysis, and machine learning to assess treatment response. Morphological features of spheroids, such as size and color intensity, are extracted and selected using the...

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Literature Corpus work: 4d33a7a7-1184-52f5-9f41-1e7a0433feb3
DOI: 10.1101/2025.03.25.645032

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