Article

Investigation of pre-existing mycobacterial immunity on the immunogenicity and efficacy of new TB vaccines

2007-01-01

Abstract excerpt

Individuals are exposed by different routes to many species of mycobacteria. In this thesis a number of murine models of mycobacterial exposure were developed, including BCG and recombinant BCG (rBCGΔUreC:Hly) primed models, environmental mycobacterial exposure models and a latent M. tuberculosis model. These models were used to assess the immunogenicity and efficacy of recombinant viral vectors expressing the M....

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Literature Corpus work: 4d29603f-4be3-5e57-8ef1-ca1b1fdc4154
DOI: 10.21954/ou.ro.0000fb4d

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