Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Recombinant BCG: innovations on an old vaccine. Scope of BCG strains and strategies to improve long-lasting memory

1 Jan 2014

Abstract excerpt

Bacille Calmette-Guérin (BCG), an attenuated vaccine derived from Mycobacterium bovis, is the current vaccine of choice against tuberculosis (TB). Despite its protection against active TB in children, BCG has failed to protect adults against TB infection and active disease development, especially in developing countries where the disease is endemic. Currently, there is a significant effort toward the development...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immune responses and vaccinations
Share to Immunodeficiency and Autoimmune Disorders
Share to Tuberculosis Research and Epidemiology

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24778634
DOI: 10.3389/fimmu.2014.00152

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Recombinant BCG: innovations on an old vaccine. Scope of BCG strains and strategies to improve long-lasting memoryPMID 24778634Read ↗

BCG VaccinesSemantic proximity Read ↗

Recombinant BCG to Enhance Its Immunomodulatory ActivitiesSemantic proximity Read ↗

Manipulation of BCG vaccine: a double-edged swordSemantic proximity Read ↗

Crucial requirement for standardization during the development of novel recombinant BCG vaccines: Does the corresponding substrain background matter?Semantic proximity Read ↗

BCG Vaccines: Their mechanisms of attenuation and impact on safety and protective efficacySemantic proximity Read ↗

Live Attenuated Vaccines against Tuberculosis: Targeting the Disruption of Genes Encoding the Secretory Proteins of MycobacteriaSemantic proximity Read ↗

Genome Sequencing and Analysis of BCG Vaccine StrainsSemantic proximity Read ↗

Genetic Modification of the BCG Vaccine to Overcome Its Limited Efficacy in Adults: A Specialized ReviewSemantic proximity Read ↗

A Mycobacterium tuberculosis-specific subunit vaccine that provides synergistic immunity upon co-administration with Bacillus Calmette-GuérinSemantic proximity Read ↗

Advances in protein subunit vaccines against tuberculosisSemantic proximity Read ↗

Live attenuated TB vaccines representing the three modern Mycobacterium tuberculosis lineages reveal that the Euro–American genetic background confers optimal vaccine potentialSemantic proximity Read ↗

Nonclinical Development of BCG Replacement Vaccine CandidatesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.