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Coronil biochemically inhibits the interaction of various clinically relevant mutants of SARS-CoV-2 Spike Proteins (Omicron Variants) with human ACE2 receptor

2024-08-19

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Accumulating evidence suggests that the receptor binding domain (RBD) of the SARS-CoV-2 Omicron variant has several times more binding affinity to the human angiotensin-converting enzyme 2 (ACE2) receptor compared to the RBD of the original covid-19 strain This increased binding affinity of Omicron variant is responsible for its increased internalization and infe...

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Literature Corpus work
4d279bbc-6a39-59ee-ba3a-4f7f08daf834
DOI
10.21203/rs.3.rs-4805471/v1
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Coronil biochemically inhibits the interaction of various clinically relevant mutants of SARS-CoV-2 Spike Proteins (Omicron Variants) with human ACE2 receptorDOI 10.21203/rs.3.rs-4805471/v1
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