Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Contributions of human ACE2 and TMPRSS2 in determining host-pathogen interaction of COVID-19.

Journal of genetics - 1 Jan 2021

Senapati Sabyasachi, Banerjee Pratibha, Bhagavatula Sandilya, Kushwaha Prem Prakash, Kumar Shashank

Abstract excerpt

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection is at present an emerging global public health crisis. Angiotensin converting enzyme 2 (ACE2) and trans-membrane protease serine 2 (TMPRSS2) are the two major host factors that contribute to the virulence of SARS-CoV-2 and pathogenesis of coronavirus disease-19 (COVID-19). Transmission of SARS-CoV-2 from animal to human is considered a rare...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiotensin-Converting Enzyme 2
Share to COVID-19 Drug Treatment

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drug Design

Share to Receptors, Virus

Share to Serine Endopeptidases

Share to Spike Glycoprotein, Coronavirus

Share to Virus Internalization

Share to Virus Release

Source

Open in PubMed Open full text

Identifiers

PMID: 33707363
PMCID: PMC7904510

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Contributions of human ACE2 and TMPRSS2 in determining host-pathogen interaction of COVID-19.PMID 33707363Read ↗

Potential COVID‐19 therapeutic approaches targeting angiotensin‐converting enzyme 2; An updated reviewSemantic proximity Read ↗

Factors regulating dynamics of angiotensin-converting enzyme-2 (ACE2), the gateway of SARS-CoV-2: Epigenetic modifications and therapeutic interventions by epidrugsSemantic proximity Read ↗

Experimental and clinical data analysis for identification of COVID-19 resistant ACE2 mutations.Semantic proximity Read ↗

Angiotensin-converting enzyme 2—at the heart of the COVID-19 pandemicSemantic proximity Read ↗

A computational and bioinformatic analysis of ACE2: an elucidation of its dual role in COVID-19 pathology and finding its associated partners as potential therapeutic targetsSemantic proximity Read ↗

ACE2 partially dictates the host range and tropism of SARS-CoV-2Semantic proximity Read ↗

A Closer Look at ACE2 Signaling Pathway and Processing during COVID-19 Infection: Identifying Possible TargetsSemantic proximity Read ↗

Variants in ACE2; potential influences on virus infection and COVID-19 severity.Semantic proximity Read ↗

ACE2 and TMPRSS2 polymorphisms in various diseases with special reference to its impact on COVID-19 disease.Semantic proximity Read ↗

Inhibition of SARS-CoV-2 pathogenesis by potent peptides designed by the mutation of ACE2 binding region.Semantic proximity Read ↗

Angiotensin Converting Enzyme 2 in Coronavirus Disease (COVID-19): Evidence from Bioinformatics AnalysisSemantic proximity Read ↗

A trimeric human angiotensin-converting enzyme 2 as an anti-SARS-CoV-2 agent in vitroSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.