Article

Systematic characterization of short intronic splicing-regulatory elements

2021-05-18

Abstract excerpt

<h4>ABSTRACT</h4> Intronic splicing enhancers and silencers (ISEs and ISSs) are two groups of splicing-regulatory elements (SREs) that play critical roles in determining splice-site selection, particularly for alternatively spliced introns or exons. SREs are often short motifs; their mutation or dysregulation of their cognate proteins frequently causes aberrant splicing and results in disease. To date, however, k...

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Literature Corpus work: 4d1fbe25-7115-5118-a0c9-fa2b6112f93d
DOI: 10.1101/2021.05.17.444464

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