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Studying the Interplay Between Apolipoprotein E and Education on Cognitive Decline in Centenarians Using Bayesian Beta Regression

2020-09-28

Abstract excerpt

Apolipoprotein E ( APOE ) is an important risk factor for cognitive decline and Alzheimer’s disease in aging individuals. Among the 3 known alleles of this gene: e2, e3, and e4, the e4 allele is associated with faster cognitive decline and increased risk for Alzheimer’s and dementia, while the e2 allele has a positive effect on longevity, and possibly on preservation of cognitive function. Education also has an im...

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Literature Corpus work
4d0bf468-6342-54ec-b6d8-49cfc134226a
DOI
10.1101/2020.09.25.20201962
Open publication

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