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Article

Effects of the APOE ε4 allele and education on cognitive function in Japanese centenarians.

Age (Dordrecht, Netherlands) - 1 Dec 2016

Ishioka Yoshiko Lily, Gondo Yasuyuki, Fuku Noriyuki, Inagaki Hiroki, Masui Yukie, Takayama Michiyo, Abe Yukiko, Arai Yasumichi, Hirose Nobuyoshi

Abstract excerpt

Apolipoprotein E (APOE) ε4 allele and education have been reported to affect the cognitive function in young-old adults. However, the effects and interactions of the ε4 allele and education on cognitive function in very old age, particularly in centenarians, are not well known. We studied 542 Japanese centenarians. Using the data in total of 452 participants (74 men and 378 women, mean age 103.6 ± 3.2 years) who...

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Identifiers

PMID: 27558117
DOI: 10.1007/s11357-016-9944-8
PMCID: PMC5266218

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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