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Article

Mapping and manipulating the Mycobacterium tuberculosis transcriptome using a transcription factor overexpression-derived regulatory network

2014-01-01

Abstract excerpt

Mycobacterium tuberculosis senses and responds to the shifting and hostile landscape of the host. To characterize the underlying intertwined gene regulatory network governed by approximately 200 transcription factors of M. tuberculosis , we have assayed the global transcriptional consequences of overexpressing each transcription factor from an inducible promoter. We cloned and overexpressed 206 transcription facto...

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Identifiers and source

Literature Corpus work
4d051e4c-181d-5b7e-956a-5c61bd00540e
DOI
10.1186/preaccept-1701638048134699
Open publication

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Mapping and manipulating the Mycobacterium tuberculosis transcriptome using a transcription factor overexpression-derived regulatory networkDOI 10.1186/preaccept-1701638048134699
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